2022 NFL Thanksgiving Day Games: Schedule, Picks, Odds, Injuries

The NFL’s Week 12 schedule for the 2022 season kicks off with three Thanksgiving games, and we’ve got everything you need to know. Our NFL Nation reporters provide us with game-by-game highlights and a bold prediction for each game.

Plus, ESPN Stats & Information provides big must-know stats and betting nuggets for each contest, and our Football Power Index (FPI) gets into the numbers with a game prediction. ESPN researcher Kyle Sope also dispenses some useful fantasy football information. Finally, Seth Walder and Eric Moody give us final score picks for all three races. Everything you want to know is here in one place to help you prepare for a busy afternoon of NFL football.

Let’s dive into the full Thanksgiving slate, including Josh Allen vs. the Lions and the NFC East matchup between the Giants and Cowboys. The football-filled celebration culminates in a Patriots-Vikings battle. Who will take another step closer to the postseason with a win on Thursday?

Go to match:
BUF-DET | NYG VALLEY | NO-MIN

12:30 PM ET | CBS | Distribution: BUF-9 (54)

What to watch for: After a 1-6 start, the red-hot Lions look to extend a rare three-game winning streak in their first nationally televised game of the season. But the Bills are one of the toughest teams in the league and are already familiar with Ford Field, having just played in the Motor City after a snowstorm forced them to switch venues in Week 11. The holiday clash could be a toss-up with the two ranked the team in the top six in points per game, yards per game and yards per game through 10 contests. — Eric Woodward

Bold prediction: Bills quarterback Josh Allen will have a complete game, throwing for over 300 yards and rushing for at least 50 more. After a rough first half against the Browns, he had a strong second half performance in the win, completing 81.8 percent of his passes and throwing for 10 .3 yards per attempt. The Lions’ defense has allowed the most yards per game (415.9) and per pass attempt (8.1) in the NFL. The Bills’ offense started moving in the right direction in the final two quarters on Sunday, and the Lions game will be a big opportunity for a full performance. — Alena Getzenberg

Stats you need to know: The Lions are looking for their third straight 30-point game, which would be their longest streak in a season since 1997. A big reason they’re putting up points is running back Jamal Williams, whose 12 rushing TDs this year are the most in the NFL and sixth most in a single season in franchise history. Williams now has five games with multiple rushing touchdowns in 2022, tied for the most in a season by a Lions player since 1950.

Injuries: Accounts | Lions

What you need to know about fantasy: Buffalo running back Devin Singletary has reached 15 fantasy points three times this season, and two of those times have come in the last two weeks. He has 133 total rushing yards (66.5 per game) and three rushing TDs over his last two games. Check out the week 12 standings.

Native Betting: Since 2004, Detroit is 3-11 against the spread and 0-14 as an underdog on Thanksgiving. Detroit’s last upset win on Thanksgiving came in 2003 against Green Bay (+7). Read more.

Thanksgiving Retrospective: On Thanksgiving Day in 1997, Detroit running back Barry Sanders rushed for 167 yards and three touchdowns against the Bears in a 55-20 win for the Lions. Read more.

Moody’s Pick: Bills 31, Lions 20
Walder’s Choice: Bills 34, Lions 17
FPI Forecast: BUF, 82.7% (average 11.2 points)

Matchup should read: Bills credit Buffalo community after win: ‘It was about you’ … Williams takes lead during Lions’ winning streak


4:30 PM ET | FOX | Distribution: DAL -9 (44.5)

What to watch for: The Cowboys have won five straight against New York at AT&T Stadium and 11 of 12 overall against their NFC East rivals. It will be the first Thanksgiving Day meeting between the two teams since 1992, a 30-3 victory for Dallas. But the holiday hasn’t been kind to the Cowboys lately. They lost three straight games on Thanksgiving Day, their longest streak since losing four in a row from 1986 to 1989. — Todd Archer

Bold prediction: Running back Jackon Barkley would rush for more than 140 yards to keep the game close. The shorthanded Giants will have no choice but to rely on Barkley even more than usual. It could work against a Dallas defense whose weakness is stopping the run. The Cowboys are ranked 26th in rushing defense (136.1 yards against per game), and Barkley already has two games of 30 or more carries and over 140 yards. Make them three. — Jordan Raanan

Stats you need to know: No quarterback has thrown for touchdowns at a higher percentage against the blitz since the start of last season than the Cowboys’ Dak Prescott (11.4%). He has thrown 25 such touchdowns in that span, most in the NFL. That could be a problem for New York on Thursday. The Giants carry the blitz at the highest rate in the NFL (43%).

Injuries: Giants | Cowboys

What you need to know about fantasy: Dallas running back Tony Pollard has gained 464 yards on his 61 touches over the last three games, while teammate Ezekiel Elliott has picked up 241 yards on his last 61 touches. Pollard also has six touchdowns in a Week 8 scrimmage, tied for the most in the NFL during that span with Jamal Williams. His four straight games with 100 yards from scrimmage are also the longest active streak in the league. Check out the week 12 standings.

I play

1:50

Stefania Bell and Field Yates break down the fantastic works of Tony Pollard and Ezekiel Eliot.

Native Betting: Since 2020, New York is 7-0 on short-rest margin — and all with Daniel Jones as the starting quarterback. Read more.

Thanksgiving Retrospective: In 1982, Giants defensive end Lawrence Taylor intercepted Lions quarterback Gary Danielson in the fourth quarter and returned it 97 yards to the house for the go-ahead — and eventual game-winning — touchdown. Read more.

Moody’s Pick: Cowboys 28, Giants 21
Walder’s Choice: Cowboys 24, Giants 20
FPI Forecast: DAL, 87.2% (average 13.6 points)

Matchup should read: What does Jones have to prove to be a part of the Giants’ future? … Where do Cowboys’ Elliott, Pollard rank among elite RB duos? … Were the Giants exposed in Week 11? … Giants WR Robinson out for season with torn ACL … What Chef Hoppy is cooking for Cowboys stars on Thanksgiving


8:20 PM ET | NBC | Distribution: MIN -2.5 (42)

What to watch for: The Patriots had their way with Vikings quarterback Kirk Cousins ​​in two games against him, beating his teams both times and holding him to an average of 5.0 yards per attempt — his lowest against any team he’s faced in very matches. This season, the Patriots are building a defense that also gives him problems. They generate pressures on 34 percent of opponents’ snaps, the third-highest percentage in the NFL. The Vikings will be without standout left tackle Christian Darrisow (concussion), and Cousins’ QBR dropped 60 points when under pressure in 2022. — Kevin Seifert

Bold prediction: Quarterback Mack Jones and the Patriots’ struggling red-zone offense — which ranks 31st in the NFL in TD percentage (12-of-28 drives, 42.9%) — will come off the drop and score two inside touchdowns at the 20-yard line. This is an area where the Vikings struggle to defend, as they rank last in the NFL in opponent touchdown percentage (20 TDs vs. 28 trips, 71.4%). — Mike Rice

Stats you need to know: The Patriots have allowed 17 or fewer points in all six of their wins this season (0-4 when allowing more than 17 points) and have now gone two straight games without allowing a touchdown. New England has gone three straight games without a TD vs. once in franchise history (2018-2019), and the Vikings failed to score a touchdown in Week 11 for the first time in their last 93 games.

Injuries: Patriots | Vikings

What you need to know about fantasy: Vikings receiver Justin Jefferson managed just 6.3 fantasy points last week in a shutout loss to the Cowboys after posting 15 in each of his previous six games. The last time he failed to catch five passes in a game was Week 3, and he followed that mistake with back-to-back double-digit catching efforts. Check out the week 12 standings.

Native Betting: Minnesota (4-5-1 ATS) and Kansas City (4-6 ATS) are the third and fourth teams in the last 20 seasons to start outright 8-2 or better but have losing records against the spread (2018 Rams , 2012 Ravens ). Read more.

Thanksgiving Retrospective: In 1998, Vikings receiver Randy Moss caught three passes for 163 yards against the Cowboys – all three of which went for touchdowns. Read more.

Moody’s Pick: Vikings 24, Patriots 14
Walder’s Choice: Vikings 27, Patriots 19
FPI Forecast: MIN, 62.6% (average 3.7 points)

Matchup should read: Patriots TD return with seconds remaining stuns Jets… After one of the worst losses ever for an 8-1 team, the Vikings’ narrative is changing again… The Patriots hope to ‘flip the switch’ in the red zone and to score more TDs … Jefferson, Vikings look to regroup after ’embarrassing’ loss

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