2023 NFL Week 16 Games: Betting Odds, Lines, Spreads & More

The NFL’s Week 16 schedule is spread over four days of action beginning Thursday with the New Orleans Saints hosting the Los Angeles Rams. Saturday will feature the Cincinnati Bengals on the road against the Pittsburgh Steelers, followed by the Buffalo Bills traveling to take on the Los Angeles Chargers. There are 10 games on Christmas Eve, culminating with the New England Patriots vs. the Denver Broncos. Finally, we have a Christmas triple-header starting with the Las Vegas Raiders vs. Kansas City Chiefs, New York Giants vs. Philadelphia Eagles, and the final game of the week will have the Baltimore Ravens traveling to Santa Clara to take on the San Francisco 49ers on Monday Night Football on ESPN and ABC. Keep checking back here for updated odds and FPI forecasts throughout the week.

Predictions from ESPN’s Football Power Index (FPI). Odds from ESPN BET.


New Orleans Saints @ Los Angeles Rams -4.5
SoFi Stadium, Inglewood, CA
Thursday 8:15pm ET


Money line: New Orleans Saints (+170); Los Angeles Rams (-200)
Total: 44.5 (fourth highest for the week)
FPI Favorite: Rams by 3.4 (60.2% to win outright)


Cincinnati Bengals -2.5 @ Pittsburgh Steelers
Acrisure Stadium, Pittsburgh
Saturday 4:30pm ET


Money line: Cincinnati Bengals (-130) ; Pittsburgh Steelers (+110)
Total: 38.5 (13th highest for the week)
FPI Favorite: Bengals by 1.5 (54.4% to win head-to-head)


Buffalo Bills -13.5 @ Los Angeles Chargers
SoFi Stadium, Inglewood, CA
Saturday 8pm ET


Money line: Buffalo Bills (-900) ; Los Angeles Chargers (+600)
Total: 42.5 (10th highest for the week)
FPI Favorite: Bills by 12 (81.8% for a complete win)


Indianapolis Colts -2.5 @ Atlanta Falcons
Mercedes-Benz Stadium, Atlanta
Sunday 1pm ET


Money line: Indianapolis Colts (-130) ; Atlanta Falcons (+110)
Total: 44.5 (fourth highest for the week)
FPI Favorite: Colts by 0.7 (52% to win outright)


Seattle Seahawks -2.5 @ Tennessee Titans
Nissan Stadium, Nashville, Tennessee
Sunday 1pm ET


Money line: Seattle Seahawks (-135) ; Tennessee Titans (+115)
Total: 42.5 (10th highest for the week)
FPI Favorite: Seahawks by 3.2 (59.6% to win head-to-head)


Detroit Lions -3.5 @ Minnesota Vikings
US Bank Stadium, Minneapolis
Sunday 1pm ET


Money line: Detroit Lions (-175) ; Minnesota Vikings (+150)
Total: 46.5 (2nd highest for the week)
FPI Favorite: Lions by 3.5 (60.6% to win head-to-head)


Washington Commanders @ New York Jets -3
MetLife Stadium, East Rutherford, NJ
Sunday 1pm ET


Money line: Washington Commanders (+135) ; New York Jets (-155)
Total: 38.5 (13th highest for the week)
FPI Favorite: Jets by 3 (59% to win outright)


Green Bay Packers -4 @ Carolina Panthers
Bank of America Stadium, Charlotte, North Carolina
Sunday 1pm ET


Money line: Green Bay Packers (-215) ; Carolina Panthers (+180)
Total: 36.5 (15th highest for the week)
FPI Favorite: Packers at 6.7 (69.5% to win head-to-head)


Cleveland Browns @ Houston Texas -2.5
NRG Stadium, Houston
Sunday 1pm ET


Money line: Cleveland Browns (+115) ; Houston Texas (-135)
Total: 42.5 (10th highest for the week)
FPI Favorite: Texans by 0.2 (50.5% to win head-to-head)


Jacksonville Jaguars @ Tampa Bay Buccaneers -0.5
Raymond James Stadium, Tampa, Florida
Sunday 4:05 PM ET


Money line: Jacksonville Jaguars (-115) ; Tampa Bay Buccaneers (-105)
Total: 43.5 (seventh highest for the week)
FPI Favorite: Jaguars by 2.5 (57.6% to win outright)


Arizona Cardinals @ Chicago Bears -4
Solder Field, Chicago
Sunday 4:25 PM ET


Money line: Arizona Cardinals (+170) ; Chicago Bears (-200)
Total: 44.5 (fourth highest for the week)
FPI Favorite: Bears by 4.1 (62.2% to win outright)


Dallas Cowboys @ Miami Dolphins -1.5
Hard Rock Stadium, Miami Gardens, Florida
Sunday 4:25 PM ET


Money line: Dallas Cowboys (+100) ; Miami Dolphins (-120)
Total: 51.5 (Highest for the week)
FPI Favorite: Cowboys by 0 (50% to win head-to-head)


New England Patriots @ Denver Broncos -5.5
Empower Field at Mile High, Denver
Sunday 8:15pm ET


Money line: New England Patriots (+225) ; Denver Broncos (-275)
Total: 36.5 (15th highest for the week)
FPI Favorite: Broncos by 5.3 (65.6% to win head-to-head)


Las Vegas Raiders @ Kansas City Chiefs -10
GEHA Field at Arrowhead Stadium, Kansas City, Missouri
Monday 1pm ET


Money line: Las Vegas Raiders (+425) ; Kansas City Chiefs (-550)
Total: 43.5 (seventh highest for the week)
FPI Favorite: Chiefs by 12.5 (82.7% to win head-to-head)


New York Giants @ Philadelphia Eagles -10.5
Lincoln Financial Field, Philadelphia
Monday 4:30pm ET


Money line: New York Giants (+425) ; Philadelphia Eagles (-550)
Total: 43.5 (seventh highest for the week)
FPI Favorite: Eagles by 15.6 (88.1% to win head-to-head)


Baltimore Ravens @ San Francisco 49ers -4.5
Levy Stadium, Santa Clara, California
Monday 8:15pm ET


Money line: Baltimore Ravens (+175) ; San Francisco 49ers (-210)
Total: 45.5 (third highest for the week)
FPI Favorite: 49ers at 4.8 (64.2% to win outright)


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