Phage technology represents ‘paradigm shift’ in skin care, says R&D expert

New York-based cosmetics and personal care ingredient manufacturer Biocogent leverages its biotech roots with its approach to targeted skin care. DermaPhage products that “are infused with a unique combination of at least three bacteriophages (or simply phages) that uniquely target a specific bacterial member of the skin microbiome…offer specificity when seeking to modulate the levels of a particular bacterial constituent of the normal skin microbiota, which can improve various skin conditions​” like acne, as detailed on the company’s website.

To learn more about topical phage therapy for cosmetic applications, including the development behind DermaPhage and the potential for further innovation using bacteriophages in skin care, CosmeticsDesign interviewed Dr. Paul Lawrence, Executive Director of Research and Discovery at Biocogent, for his insights.

CDU: What is the potential impact of technological development and phage release on manufacturers and suppliers in the cosmetics and personal beauty care industry?

Dr. Paul Lawrence (Poland): In an era of increasing antimicrobial resistance, the antibacterial bacteriophage platform has the potential to be transformative in many ways. This technology provides an alternative to the prescription of topical antibiotics for the treatment of many skin diseases caused by bacteria, which does not have an accompanying negative impact on the beneficial members of the microbiota.

Furthermore, as our understanding continues to grow of the importance of the skin microbiome in relation to skin health, so will the desire to use this knowledge to develop and commercialize more “microbiome-modulating” cosmetic care products in hopes of improving many skin conditions that are a bacterial culprit. The beauty of bacteriophages is their species specificity – they target only one bacterial species (sometimes even one strain of a particular species).

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