Mice study shows that nose collection has a surprising relationship with Alzheimer’s disease

2022 The published study identified a poor but reliable relationship between nasal choice and increased risk of dementia.

In cases where the choice of the nose causes internal tissue damage, the critical types of bacteria have a clearer path to the brain, which responds to their presence in a way that resembles signs of Alzheimer’s disease.

There are many warnings here, of which it is equally important that the research that still supports is not in the mouse, not humans, but the conclusions are definitely worth a further study – and could improve our understanding of how Alzheimer’s disease begins, which remains a mystery.

Related: Alzheimer’s breakthrough: Lithium’s losing mouse memory loss

A team of researchers led by scientists from Griffith University in Australia Chlamydia pneumoniaewhich can infect people and cause pneumonia.

Bacteria were also found in most human brain affected by late dementia.

It has been proven that mice bacteria could take the olfactory nerve (connecting the nasal cavity and brain). In addition, when the nasal epithelium (thin tissue along the roof of the nasal cavity) was damaged, the nerve infection deteriorated.

This prompted the mouse’s brain to deposit more amyloid-beta protein-whiteness, which is distinguished by responding to infections. This protein plaques (or clumps) are also present at high concentrations for people with Alzheimer’s disease.

Illustration of Amyloid-Beta protein plates in orange. (NIH/FLICKR/PD)

“We’re the first to show that Chlamydia pneumoniae Can go straight to the nose and to the brain where it can eliminate pathologies that look like Alzheimer’s disease, ”said neuromoxy James St John of Griffith University in Australia as early as October 2022, when a study was launched.

“We have seen it happened in the mouse model, and the evidence can be terrible to people too.”

Scientists were surprised by the speed of which C. Pneumoniae Adopted in the central nervous system of mice, infection occurs within 24-72 hours. Bacteria and viruses are believed to see the nose as a fast path to the brain.

Although it is unknown that the effect of humans will be the same, or even the amyloid-beth plates are Alzheimer’s disease, it is still important to follow promising potential customers to understand this overall neurodegenerative condition.

“We have to do this study with people and confirm whether the same path works the same way,” said Stohn.

“These are research offered by many people, but have not yet been completed. We know that the same bacteria are humans, but we have not found out how they will get there.”

Collecting a nose is not exactly rare. In fact, it can do it as many as 9 out of 10 people … Not to mention many other types (some slightly more skilled than others). Although the advantages are not clear, research like this should take us a pause before collecting.

The child collects the nose

Future research on the same people’s processes is planned, but John and his colleagues show that choosing a nose and carrying nose hair “is not a good idea” due to the possible damage she does due to the protective nasal tissue.

One exclusive question the team wants to answer is whether the increased amyloid-beta protein sediment is a natural, healthy immune response that can be replaced when the infection is fought.

Alzheimer’s disease is an incredibly complex disease, as can be seen from many studies, and many different angles that scientists try to understand it, but each part of the research brings us closer to how to find a way to stop it.

“When you are over 65, your risk factor increases, but we also look at other reasons, because it’s not just age – it’s also an environmental impact,” said St John.

“And we think bacteria and viruses are critical.”

The investigation has been published Scientific reports;

The version of this article was first published in 2022. November

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