Some immunization can quietly protect us from cognitive decline.
The way the medicine can do is the mystery scientists who want to solve it. A new study of two older adult vaccines gives us an essential hint.
More than 130,000 people participated in the Retrospective Cohort study. This reveals that tape herpes vaccine (known as SHINGRIX) and respiratory synticitis virus (RSV) vaccine (AREXYV) is associated with reduced risk of dementia compared to the annual influenza vaccine.
Related: A new study associates regular medicines with reduced risk of dementia
Both Shingrix and Arexyv are recommended for older adults and contain AS01 Adjuvant, which helps stimulate the immune system after vaccination. The influenza vaccine does not.
Because the relationship with dementia was observed shortly after the JAB was obtained, it is unlikely that the protection of vaccines against the direct effect of the virus is behind dementia.
Instead, Oxford’s findings show that “AS01 Adjuvant himself plays a direct role in reducing the risk of dementia.”
In 18 months after receiving the SHINGRIX vaccine, participants showed a 18 percent reduced risk of dementia compared to those who were only vaccinated with the flu vaccine.
Meanwhile, for those undergoing RSV vaccine, the risk of dementia decreased by 29 percent compared to the flu vaccine.
Participants were given to both the Shingrix and the Arexyv vaccine decreased by 37 percent. Risk.
This general effect was not statistically higher than one vaccine. In other words, protection against two viruses did not significantly increase protection against dementia.
The results show that some vaccines “protect against dementia through mechanisms unrelated to (or at least) their prevention [target virus]“Write the authors of the study led by psychiatrist Maxime Taquet of Oxford University.
If this is true, then certain vaccines can protect against dementia by causing important immune system roads.
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Conclusions correspond to the emerging hypothesis: that dementia is actually not a brain disease, but a brain immune disorder.
Perhaps vaccines can help you start and act again, even if the threatening virus never occurs.
In recent years, studies have shown that several common viruses, such as cold sores, herpes, mono, pneumonia and Covidid-19, can cause a greater risk of cognitive decline. In addition, vaccines seem to reduce this risk in large quantities.
But why was it a mystery.
For example, in 2024. The United Kingdom study found that SHINGRIX defined the onset of dementia by 17 percent compared to older, less effective tape herpes vaccines.
At that time, this was interpreted as it indicates that the more effective herpes vaccine reduces the effect of the virus, the more the brain is protected from cognitive decline.
However, this older version of herpes vaccines (called Zostavax) does not include the AS01 immunity amplifier, which may have affected the results.
In the US, it is usually recommended that two doses of herpes vaccine be used for adults over 50 years to protect against Varicella-Zoster virus. It is the same virus that causes chicken pox, and it can be latent in the brain for many years before the adults begin to appear again.
It is also recommended that adults over 75 years of age receive a RSV vaccine.
Both of these vaccines can protect against dangerous infections, but it seems that it may not be everything.
“It is likely that both AS01 strip and RSV vaccines provide some protection against dementia,” Taquet and his colleagues conclude.
“The mechanisms based on this protection must still be determined.”
Vaccines have saved stunning 154 million lives worldwide in the last half of the year.
If we are lucky, it is just the tip of the iceberg.
The investigation has been published In the case of vaccines;