The trip to space is cruel on the body.
Astronauts can lose density, their brain and eye nerves to swell and their genes change the resolution due to space flight. Studies show that skipping in space is similar to rapid aging.
NASA’s innovative research on identical double astronauts Mark and Scott Kelly watched both men’s aging signals while Mark stayed on Earth and Scott spent 340 days in space.
Based on 2019 The Gemini Research, published in Science, Science Science, was published in 2019. The “twin study” published in Science remained even six months later, as DNA lesions, reduced cognitive function and shortened by telomeres.
A study published in the Journal Cell stem cell now describes a new discovery on Thursday – that stem cells show signs of aging and during stress.
In fact, they are aging “ten times faster in space than on the ground,” said Dr. Catriona Jamieson, San Diego, University of Sanfor University of California, the main author of the study, director of the Sanford Stem Cell Institute.
Stem cells are special cells that can develop into various tissues. Stem cell aging can cause anxiety as it reduces the natural ability of the body to repair tissues and organs that can cause chronic, age -related conditions such as cancer, neurodegenerative diseases and heart problems.
The new study is at the time of increasing interest in SpaceFlight. Governments are planning long -term missions to the moon, and private companies begin consumers and celebrities into space. It is important to understand the risk of health so that travel in space is safer. August in aging cells could also help researchers better understand how the biological processes occur slower, here on Earth.
Astronauts and twins Scott and Mark Kelly 2016 NASA’s Johnson Space Center (Houston Chronicle / Hearst NewsPap / Houston Chronicle via Getty Imag)
Investigators collected stem cells from the bone marrow donated by people who underwent hip replacement surgery. Cells were considered “nanobioreactors” inside, which are essentially small, transparent blood bags that are not larger than the iPhone, where biological processes could take place. Nanobioreactors were placed in a box built for cells called Kubelab.
Each patient’s sample was divided into two kubelab, one for space and the other remaining on Earth.
In four commercial SpaceX missions, which SpaceX to the International Space Station, spaces related to space were launched. In total, the samples spent 32 to 45 days on SpaceX spacecraft, giving cells to microgravitis or weightless orbit for more than a month. For comparison, researchers used cells in Cubelab sections on the ground.
Cubelab watched cells during travel and overhead stays, depicting their microscope every day. When space stem cells returned to the ground, researchers compared those samples to their “land controls”, follow their genomes and perform other tests.
The SpaceX Falcon 9 rocket rises from NASA Kennedy Space Center Florida in 2023. March 14th. (SpaceX)
Researchers examined seven signs of aging in stem cells and found clear signs of aging Those It went into space, including more inflammatory alarm and less telomere support, the protective ends of the chromosomes that prevents DNA breaks. They also noted that the genome instability has increased or the replication errors in the genetic code have increased, which can cause mutations.
“This is probably the most comprehensive exam I have seen from the signatures of some space flight,” said Christopher Mason, Weil Cornell Medical Geneticist in New York, who was the author of the TWins research, but did not participate in new research. “This is definitely evidence of some aging.”
He said Jamieson’s work “is based and then expands” what his team found in the study of Kelly twins, including the fact that SpaceFlight causes a rapid immune response to a molecular level.
New studies could eventually help researchers create a future treatment that could be useful for both astronauts and people who want to be firmly planted in the ground, setting new mechanisms of age -related diseases, Jamieson said. These conditions are becoming increasingly common as the world’s population is aging and the birth rate is decreasing.
“Forecasting of stem cell aging, preventing and changing stress or inflammation we go,” Jamieson said.
This article was originally published in nbcnews.com